Low Density Lipoprotein Receptor-related Protein Mediates Endocytic Clearance of Pro-MMP-2·TIMP-2 Complex through a Thrombospondin-independent Mechanism
The low density lipoprotein receptor-related protein (LRP) mediates the endocytic clearance of various proteinases and proteinase·inhibitor complexes, including thrombospondin (TSP)-dependent endocytosis of matrix metalloproteinase (MMP)-2 (or gelatinase A), a key effector of extracellular matrix re...
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Veröffentlicht in: | The Journal of biological chemistry 2004-12, Vol.279 (52), p.54944-54951 |
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Hauptverfasser: | , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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