Tec Kinases Mediate Sustained Calcium Influx via Site-specific Tyrosine Phosphorylation of the Phospholipase Cγ Src Homology 2-Src Homology 3 Linker

Tyrosine phosphorylation of phospholipase Cγ2 (PLCγ2) is a crucial activation switch that initiates and maintains intracellular calcium mobilization in response to B cell antigen receptor (BCR) engagement. Although members from three distinct families of non-receptor tyrosine kinases can phosphoryla...

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Veröffentlicht in:	The Journal of biological chemistry 2004-09, Vol.279 (36), p.37651-37661
Hauptverfasser:	Humphries, Lisa A., Dangelmaier, Carol, Sommer, Karen, Kipp, Kevin, Kato, Roberta M., Griffith, Natasha, Bakman, Irene, Turk, Christoph W., Daniel, James L., Rawlings, David J.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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