The SNARE Motif Contributes to rbet1 Intracellular Targeting and Dynamics Independently of SNARE Interactions

The endoplasmic reticulum/Golgi SNARE rbet1 cycles between the endoplasmic reticulum and Golgi and is essential for cargo transport in the secretory pathway. Although the quaternary SNARE complex containing rbet1 is known to function in membrane fusion, the structural role of rbet1 is unclear. Furth...

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Veröffentlicht in:	The Journal of biological chemistry 2003-04, Vol.278 (16), p.14121-14133
Hauptverfasser:	Joglekar, Ashwini P., Xu, Dalu, Rigotti, Daniel J., Fairman, Robert, Hay, Jesse C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Motifs Amino Acid Sequence Animals Cell Line Cytoplasm - metabolism Dose-Response Relationship, Drug Endoplasmic Reticulum - metabolism Golgi Apparatus - metabolism Membrane Proteins - chemistry Membrane Proteins - metabolism Membrane Proteins - pharmacology Microscopy, Fluorescence Molecular Sequence Data Mutation Nerve Tissue Proteins - metabolism Precipitin Tests Protein Binding Protein Structure, Quaternary Protein Structure, Tertiary Qa-SNARE Proteins Qb-SNARE Proteins Qc-SNARE Proteins Rats Sequence Homology, Amino Acid SNARE Proteins Synaptosomal-Associated Protein 25 Time Factors Transfection Ultracentrifugation Vesicular Transport Proteins - metabolism
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