Dysregulated Ryanodine Receptors Mediate Cellular Toxicity

Ca2+ homeostasis is a vital cellular control mechanism in which Ca2+ release from intracellular stores plays a central role. Ryanodine receptor (RyR)-mediated Ca2+ release is a key modulator of Ca2+ homeostasis, and the defective regulation of RyR is pathogenic. However, the molecular events underly...

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Veröffentlicht in:	The Journal of biological chemistry 2003-08, Vol.278 (31), p.28856-28864
Hauptverfasser:	George, Christopher H., Higgs, Gemma V., Mackrill, John J., Lai, F.Anthony
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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