GLFG and FxFG Nucleoporins Bind to Overlapping Sites on Importin-β

The interaction between nuclear pore proteins (nucleoporins) and transport factors is crucial for the translocation of macromolecules through nuclear pores. Many nucleoporins contain FG sequence repeats, and previous studies have demonstrated interactions between repeats containing FxFG or GLFG core...

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Veröffentlicht in:	The Journal of biological chemistry 2002-12, Vol.277 (52), p.50597-50606
Hauptverfasser:	Bayliss, Richard, Littlewood, Trevor, Strawn, Lisa A., Wente, Susan R., Stewart, Murray
Format:	Artikel
Sprache:	eng
Schlagworte:	Active Transport, Cell Nucleus Amino Acid Sequence Animals beta Karyopherins - chemistry beta Karyopherins - genetics beta Karyopherins - metabolism Binding Sites Cloning, Molecular Crystallography, X-Ray Dogs Kinetics Models, Molecular Nuclear Pore Complex Proteins - chemistry Nuclear Pore Complex Proteins - metabolism Peptide Fragments - chemistry Peptide Fragments - metabolism Protein Conformation Protein Structure, Secondary Recombinant Proteins - chemistry Recombinant Proteins - metabolism Saccharomyces cerevisiae - genetics
Online-Zugang:	Volltext
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