Ca2+-dependent Dephosphorylation of Kinesin Heavy Chain on β-Granules in Pancreatic β-Cells

The specific biochemical steps required for glucose-regulated insulin exocytosis from β-cells are not well defined. Elevation of glucose leads to increases in cytosolic [Ca2+] i and biphasic release of insulin from both a readily releasable and a storage pool of β-granules. The effect of elevated [C...

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Veröffentlicht in:	The Journal of biological chemistry 2002-07, Vol.277 (27), p.24232-24242
Hauptverfasser:	Donelan, Matthew J., Morfini, Gerardo, Julyan, Richard, Sommers, Scott, Hays, Lori, Kajio, Hiroshi, Briaud, Isabelle, Easom, Richard A., Molkentin, Jeffery D., Brady, Scott T., Rhodes, Christopher J.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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