Molecular Basis for the Protein Recognition Specificity of the Dynein Light Chain DYNLT1/Tctex1

It has been suggested that DYNLT1, a dynein light chain known to bind to various cellular and viral proteins, can function both as a molecular clamp and as a microtubule-cargo adapter. Recent data have shown that the DYNLT1 homodimer binds to two dynein intermediate chains to subsequently link cargo...

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Veröffentlicht in:	The Journal of biological chemistry 2016-09, Vol.291 (40), p.20962-20975
Hauptverfasser:	Merino-Gracia, Javier, Zamora-Carreras, Héctor, Bruix, Marta, Rodríguez-Crespo, Ignacio
Format:	Artikel
Sprache:	eng
Schlagworte:	activin dynein microtubule nuclear magnetic resonance (NMR) protein chemistry transforming growth factor β (TGF-β) transport
Online-Zugang:	Volltext
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