Elucidating the Role of Disulfide Bond on Amyloid Formation and Fibril Reversibility of Somatostatin-14

The storage of protein/peptide hormones within subcellular compartments and subsequent release are crucial for their native function, and hence these processes are intricately regulated in mammalian systems. Several peptide hormones were recently suggested to be stored as amyloids within endocrine s...

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Veröffentlicht in:The Journal of biological chemistry 2014-06, Vol.289 (24), p.16884-16903
Hauptverfasser: Anoop, Arunagiri, Ranganathan, Srivastav, Dhaked, Bhagwan Das, Jha, Narendra Nath, Pratihar, Supriya, Ghosh, Saikat, Sahay, Shruti, Kumar, Santosh, Das, Subhadeep, Kombrabail, Mamata, Agarwal, Kumud, Jacob, Reeba S., Singru, Praful, Bhaumik, Prasenjit, Padinhateeri, Ranjith, Kumar, Ashutosh, Maji, Samir K.
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Sprache:eng
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