Up-regulation of the Neuronal Nicotinic Receptor α7 by HIV Glycoprotein 120

Approximately 30–50% of the >30 million HIV-infected subjects develop neurological complications ranging from mild symptoms to dementia. HIV does not infect neurons, and the molecular mechanisms behind HIV-associated neurocognitive decline are not understood. There are several hypotheses to expla...

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Veröffentlicht in:	The Journal of biological chemistry 2012-01, Vol.287 (5), p.3079-3086
Hauptverfasser:	Ballester, Leomar Y., Capó-Vélez, Coral M., García-Beltrán, Wilfredo F., Ramos, Félix M., Vázquez-Rosa, Edwin, Ríos, Raymond, Mercado, José R., Meléndez, Roberto I., Lasalde-Dominicci, José A.
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS Chemokines CHRNA7 CXCR4 GP120 HAND HIV NeuroAIDS Neuroblastoma Nicotinic Acetylcholine Receptors
Online-Zugang:	Volltext
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