Phosphorylation of STAT-3 in Response to Basic Fibroblast Growth Factor Occurs through a Mechanism Involving Platelet-activating Factor, JAK-2, and Src in Human Umbilical Vein Endothelial Cells

Platelet-activating factor (PAF) is a potent proinflammatory phospholipid with multiple pathological and physiological effects. We have shown that basic fibroblast growth factor (bFGF) supplementation induces rapid proliferation of human umbilical vein endothelial cells (HUVEC), which is reduced upo...

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Veröffentlicht in:	The Journal of biological chemistry 2002-06, Vol.277 (24), p.21237-21245
Hauptverfasser:	Deo, Dayanand D., Axelrad, T. William, Robert, Everett G., Marcheselli, Victor, Bazan, Nicolas G., Hunt, Jay D.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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