The Hepatitis B Virus-X Protein Activates a Phosphatidylinositol 3-Kinase-dependent Survival Signaling Cascade

The hepatitis B virus-X (HBx) protein is known as a multifunctional protein that not only coactivates transcription of viral and cellular genes but coordinates the balance between proliferation and programmed cell death, by inducing or blocking apoptosis. In this study the role of the HBx protein in...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of biological chemistry 2001-05, Vol.276 (20), p.16969-16977
Hauptverfasser:	Lee, Yoon Ik, Kang-Park, Sukmi, Do, Su-Il, Lee, Young Ik
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis - drug effects Apoptosis - physiology bcl-Associated Death Protein Carrier Proteins - metabolism Cell Division - drug effects Cell Line Cell Line, Transformed Cell Nucleus - ultrastructure Cell Survival - drug effects Cell Survival - physiology Culture Media, Serum-Free Etoposide - pharmacology Hepatitis B Antigens - metabolism Hepatitis B virus - physiology Humans Kinetics Liver - cytology Liver - physiology Liver - virology Phosphatidylinositol 3-Kinases - metabolism Phosphorylation Protein-Serine-Threonine Kinases Proto-Oncogene Proteins - metabolism Proto-Oncogene Proteins c-akt Recombinant Proteins - metabolism Signal Transduction - physiology Staurosporine - pharmacology Trans-Activators - metabolism Transfection Viral Regulatory and Accessory Proteins
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!