Uncoupling of 3′-Phosphatase and 5′-Kinase Functions in Budding Yeast
Polynucleotide kinase is a bifunctional enzyme containing both DNA 3′-phosphatase and 5′-kinase activities seemingly suited to the coupled repair of single-strand nicks in which the phosphate has remained with the 3′-base. We show that the yeastSaccharomyces cerevisiae is able to repair transformed...
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| Veröffentlicht in: | The Journal of biological chemistry 2001-01, Vol.276 (18), p.15073-15081 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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