Tissue Factor Pathway Inhibitor Inhibits Endothelial Cell Proliferation via Association with the Very Low Density Lipoprotein Receptor

Tissue factor pathway inhibitor (TFPI) contains three Kunitz-type proteinase inhibitor domains and is a potent inhibitor of tissue factor-mediated coagulation. Here, we report that TFPI inhibits the proliferation of basic fibroblast growth factor-stimulated endothelial cells. A truncated form of TFP...

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Veröffentlicht in:	The Journal of biological chemistry 2001-04, Vol.276 (15), p.12241-12248
Hauptverfasser:	Hembrough, Todd A., Ruiz, Jose F., Papathanassiu, Adonia E., Green, Shawn J., Strickland, Dudley K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies - immunology Cell Division - drug effects Cell Division - immunology Cells, Cultured Endothelium, Vascular - cytology Endothelium, Vascular - drug effects Humans Lipoproteins - chemistry Lipoproteins - metabolism Lipoproteins - pharmacology Protein Binding Receptors, LDL - immunology Receptors, LDL - metabolism
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