Protein Kinase C Phosphorylates RGS2 and Modulates Its Capacity for Negative Regulation of Gα11 Signaling

RGS proteins (regulators of G protein signaling) attenuate heterotrimeric G protein signaling by functioning as both GTPase-activating proteins (GAPs) and inhibitors of G protein/effector interaction. RGS2 has been shown to regulate Gαq-mediated inositol lipid signaling. Although purified RGS2 block...

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Veröffentlicht in:The Journal of biological chemistry 2001-02, Vol.276 (8), p.5438-5444
Hauptverfasser: Cunningham, Michelle L., Waldo, Gary L., Hollinger, Susanne, Hepler, John R., Harden, T.Kendall
Format: Artikel
Sprache:eng
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