The Role of N-Glycosylation in Transport to the Plasma Membrane and Sorting of the Neuronal Glycine Transporter GLYT2

Glycine transporter GLYT2 is an axonal glycoprotein involved in the removal of glycine from the synaptic cleft. To elucidate the role of the carbohydrate moiety on GLYT2 function, we analyzed the effect of the disruption of the putativeN-glycosylation sites on the transport activity, intracellular t...

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Veröffentlicht in:	The Journal of biological chemistry 2001-01, Vol.276 (3), p.2168-2173
Hauptverfasser:	Martı́nez-Maza, Rodrigo, Poyatos, Irene, López-Corcuera, Beatriz, Núñez, Enrique, Giménez, Cecilio, Zafra, Francisco, Aragón, Carmen
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Transport Systems, Neutral Animals Carrier Proteins - chemistry Carrier Proteins - metabolism Cell Line Cell Membrane - metabolism Cricetinae Glycine Plasma Membrane Transport Proteins Glycosylation Neurons - metabolism Protein Conformation Protein Sorting Signals Protein Transport
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