Bcl-2 Independence of Flavopiridol-induced Apoptosis

The new chemotherapeutic agent, flavopiridol, presently in clinical trials, has been extensively studied yet little is known about its mechanism of action. In this study we show that the induction of apoptosis by flavopiridol is largely independent of Bcl-2. This is indicated by the observation that...

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Veröffentlicht in:	The Journal of biological chemistry 2000-10, Vol.275 (41), p.32089-32097
Hauptverfasser:	Achenbach, Tatjana V., Müller, Rolf, Slater, Emily P.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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