Novel Single Chain cAMP Sensors for Receptor-induced Signal Propagation

cAMP is a universal second messenger of many G-protein-coupled receptors and regulates a wide variety of cellular events. cAMP exerts its effects via cAMP-dependent protein kinase (PKA), cAMP-gated ion channels, and two isoforms of exchange protein directly activated by cAMP (Epac). Here we report t...

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Veröffentlicht in:	The Journal of biological chemistry 2004-09, Vol.279 (36), p.37215-37218
Hauptverfasser:	Nikolaev, Viacheslav O., Bünemann, Moritz, Hein, Lutz, Hannawacker, Annette, Lohse, Martin J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Cricetinae Cyclic AMP - metabolism Fluorescence Humans Second Messenger Systems Signal Transduction
Online-Zugang:	Volltext
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