ΔFosB: A Sustained Molecular Switch for Addiction

The longevity of some of the behavioral abnormalities that characterize drug addiction has suggested that regulation of neural gene expression may be involved in the process by which drugs of abuse cause a state of addiction. Increasing evidence suggests that the transcription factor ΔFosB represent...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2001-09, Vol.98 (20), p.11042-11046
Hauptverfasser:	Nestler, Eric J., Barrot, Michel, Self, David W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Addiction Behavioral neuroscience Cocaine Colloquium: Neural Signing. Papers from the Inaugural Arthur M. Sackler Colloquium of the National Academy of Sciences DFosB protein FosB gene FosB protein Genes Medication administration Mice Neurons Nucleus accumbens Protein isoforms Transcription factors
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