Sensing of latent EBV infection through exosomal transfer of 5′pppRNA

Complex interactions between DNA herpesviruses and host factors determine the establishment of a life-long asymptomatic latent infection. The lymphotropic Epstein–Barr virus (EBV) seems to avoid recognition by innate sensors despite massive transcription of immunostimulatory small RNAs (EBV-EBERs)....

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2016-02, Vol.113 (5), p.E587-E596
Hauptverfasser:	Baglio, S. Rubina, van Eijndhoven, Monique A. J., Koppers-Lalic, Danijela, Berenguer, Jordi, Lougheed, Sinéad M., Gibbs, Susan, Léveillé, Nicolas, Rinkel, Rico N. P. M., Hopmans, Erik S., Swaminathan, Sankar, Verkuijlen, Sandra A. W. M., Scheffer, George L., van Kuppeveld, Frank J. M., de Gruijl, Tanja D., Bultink, Irene E. M., Jordanova, Ekaterina S., Hackenberg, Michael, Piersma, Sander R., Knol, Jaco C., Voskuyl, Alexandre E., Wurdinger, Thomas, Jiménez, Connie R., Middeldorp, Jaap M., Pegtel, D. Michiel
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Sciences PNAS Plus
Online-Zugang:	Volltext
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