A ΩX a V motif in the Rift Valley fever virus NSs protein is essential for degrading p62, forming nuclear filaments and virulence

Infection with the Rift Valley fever virus (RVFV) has the capacity to cause fatal hemorrhagic fever in humans. A unique characteristic of RVFV infection is the presence of nuclear filaments whose formation is linked to synthesis of the viral NSs protein. We identify a crucial interaction between a Ω...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2015-05, Vol.112 (19), p.6021-6026
Hauptverfasser:	Cyr, Normand, de la Fuente, Cynthia, Lecoq, Lauriane, Guendel, Irene, Chabot, Philippe R., Kehn-Hall, Kylene, Omichinski, James G.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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