Thermodynamic mechanism for inhibition of lactose permease by the phosphotransferase protein IIA Glc

Carbohydrate uptake in many bacteria is regulated by the phosphotransferase protein IIA Glc , enabling cells to use glucose preferentially over other sugars. Lactose permease (LacY) is one of many sugar permeases regulated by IIA Glc , but the mechanism of inducer exclusion is unclear. We now show b...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2015-02, Vol.112 (8), p.2407-2412
Hauptverfasser:	Hariharan, Parameswaran, Balasubramaniam, Dhandayuthapani, Peterkofsky, Alan, Kaback, H. Ronald, Guan, Lan
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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