Activation of protein synthesis in mouse uterine epithelial cells by estradiol-17β is mediated by a PKC–ERK1/2–mTOR signaling pathway

The uterine epithelium of mice and humans undergoes cyclical waves of cell proliferation and differentiation under the regulation of estradiol-17β (E ₂) and progesterone (P ₄). These epithelial cells respond to E ₂ with increased protein and DNA synthesis, whereas P ₄ inhibits only the E ₂-induced D...

Ausführliche Beschreibung