Holo-TFIID controls the magnitude of a transcription burst and fine-tuning of transcription

Transcription factor (TF)IID is a central player in activated transcription initiation. Recent evidence suggests that the role and composition of TFIID are more diverse than previously understood. To investigate the effects of changing the composition of TFIID in a simple system, we depleted TATA bo...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2013-05, Vol.110 (19), p.7678-7683
Hauptverfasser:	Pennington, Katie L., Marr, Sharon K., Chirn, Gung-Wei, Marr, Michael T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Sciences Cadmium - pharmacology Cell lines Cells Copper - pharmacology Datasets DNA DNA-Directed RNA Polymerases - metabolism Drosophila Drosophila melanogaster - genetics Drosophila melanogaster - metabolism Drosophila Proteins - genetics Drosophila Proteins - metabolism Escherichia coli - metabolism Gene Expression Profiling Gene Expression Regulation Genes Genome Hepatocytes Histone Acetyltransferases - genetics Histone Acetyltransferases - metabolism Insects Messenger RNA metallothionein Metallothionein - metabolism Proteins RNA RNA Interference RNA polymerase RNA, Messenger - metabolism Somatic cells Stem cells TATA-Binding Protein Associated Factors transcription (genetics) Transcription Factor TFIID - genetics Transcription Factor TFIID - metabolism transcription factors Transcription, Genetic
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