Amygdala lesions disrupt modulation of functional MRI activity evoked by facial expression in the monkey inferior temporal cortex
Significance Successful social interaction depends on the ability to recognize others, evaluate their mental states (e.g. intentions, desires, and beliefs), and “read” their emotional states. Here, we show that, in monkeys, damage to the amygdala, a brain structure that is central to the expression...
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| Veröffentlicht in: | Proceedings of the National Academy of Sciences - PNAS 2012-12, Vol.109 (52), p.E3640-E3648 |
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| container_title | Proceedings of the National Academy of Sciences - PNAS |
| container_volume | 109 |
| creator | Hadj-Bouziane, Fadila Liu, Ning Bell, Andrew H Gothard, Katalin M Luh, Wen-Ming Tootell, Roger B H Murray, Elisabeth A Ungerleider, Leslie G |
| description | Significance Successful social interaction depends on the ability to recognize others, evaluate their mental states (e.g. intentions, desires, and beliefs), and “read” their emotional states. Here, we show that, in monkeys, damage to the amygdala, a brain structure that is central to the expression of emotion, significantly disrupts the processing of emotional facial expression in high-level visual cortical areas involved in face recognition. These findings suggest that the projections of the amygdala to visual cortical areas likely enhance the sensory processing of biologically important signals, including those related to potential environmental threats and social contexts. |
| doi_str_mv | 10.1073/pnas.1218406109 |
| format | Article |
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These findings suggest that the projections of the amygdala to visual cortical areas likely enhance the sensory processing of biologically important signals, including those related to potential environmental threats and social contexts.</description><subject>amygdala</subject><subject>Amygdala - pathology</subject><subject>Amygdala - physiopathology</subject><subject>Animal behavior</subject><subject>Animal cognition</subject><subject>Animals</subject><subject>Biological Sciences</subject><subject>Brain</subject><subject>Brain Mapping</subject><subject>cortex</subject><subject>Evoked Potentials - physiology</subject><subject>face</subject><subject>Facial Expression</subject><subject>Life Sciences</subject><subject>Macaca mulatta - physiology</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>monkeys</subject><subject>Monkeys & apes</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>PNAS Plus</subject><subject>Temporal Lobe - physiopathology</subject><issn>0027-8424</issn><issn>1091-6490</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFksFu1DAQhiMEokvhzA0scYHDtmM7sZML0qpqaaVFSEDPltcZ77pN4mAnq-6RN6-jXVrohYvtmfnmn7E9WfaWwgkFyU_7TscTymiZg6BQPctmaaVzkVfwPJsBMDkvc5YfZa9ivAGAqijhZXbEeMqoJJtlvxftbl3rRpMGo_NdJLWLYewH0vp6bPSQfMRbYsfOTGfdkK_fr4hOxtYNO4Jbf4s1We2I1calKN71AeMkRVxHhg0moe4Wd8myGJwPZMC29yGhxocB715nL6xuIr457MfZ9cX5z7PL-fLbl6uzxXJuBPBhbldC66qyWjLMeSG1NWhLljMG3BQoa1Ej5bambKWBWymlBkTDTE0pK4zkx9nnvW4_rlqsDXZDakL1wbU67JTXTv0b6dxGrf1W8YIXAsok8GkvsHmSdrlYqskHHGgueLGlif14KBb8rxHjoFoXDTaN7tCPUdESOGW55OL_KJOc56IoqoR-eILe-DGkP5kokZosJJ0uerqnTPAxBrQPzVJQ09SoaWrU49SkjHd_P80D_2dMEkAOwJT5KFepgqlzLnJIyPs9YrVXeh1cVNc_GFABQLkUqco9d_nT8Q</recordid><startdate>20121226</startdate><enddate>20121226</enddate><creator>Hadj-Bouziane, Fadila</creator><creator>Liu, Ning</creator><creator>Bell, Andrew H</creator><creator>Gothard, Katalin M</creator><creator>Luh, Wen-Ming</creator><creator>Tootell, Roger B H</creator><creator>Murray, Elisabeth A</creator><creator>Ungerleider, Leslie G</creator><general>National Academy of Sciences</general><general>National Acad Sciences</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7QL</scope><scope>7QP</scope><scope>7QR</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TK</scope><scope>7TM</scope><scope>7TO</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><scope>7S9</scope><scope>L.6</scope><scope>1XC</scope><scope>VOOES</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-2778-002X</orcidid><orcidid>https://orcid.org/0000-0002-5415-7949</orcidid></search><sort><creationdate>20121226</creationdate><title>Amygdala lesions disrupt modulation of functional MRI activity evoked by facial expression in the monkey inferior temporal cortex</title><author>Hadj-Bouziane, Fadila ; 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| source | Jstor Complete Legacy; MEDLINE; PubMed Central; Alma/SFX Local Collection; Free Full-Text Journals in Chemistry |
| subjects | amygdala Amygdala - pathology Amygdala - physiopathology Animal behavior Animal cognition Animals Biological Sciences Brain Brain Mapping cortex Evoked Potentials - physiology face Facial Expression Life Sciences Macaca mulatta - physiology Magnetic Resonance Imaging Male monkeys Monkeys & apes NMR Nuclear magnetic resonance PNAS Plus Temporal Lobe - physiopathology |
| title | Amygdala lesions disrupt modulation of functional MRI activity evoked by facial expression in the monkey inferior temporal cortex |
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