Tfb6, a previously unidentified subunit of the general transcription factor TFIIH, facilitates dissociation of Ssl2 helicase after transcription initiation

General transcription factor TFIIH, previously described as a 10-subunit complex, is essential for transcription and DNA repair. An eleventh subunit now identified, termed Tfb6, exhibits 45% sequence similarity to human nuclear mRNA export factor 5. Tfb6 dissociates from TFIIH as a heterodimer with...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2012-03, Vol.109 (13), p.4816-4821
Hauptverfasser: Murakami, Kenji, Gibbons, Brian J, Davis, Ralph E, Nagai, Shigeki, Liu, Xin, Robinson, Philip J. J, Wu, Tinghe, Kaplan, Craig D, Kornberg, Roger D
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Sprache:eng
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