Schizophrenia susceptibility gene dysbindin regulates glutamatergic and dopaminergic functions via distinctive mechanisms in Drosophila
The dysfunction of multiple neurotransmitter systems is a striking pathophysiological feature of many mental disorders, schizophrenia in particular, but delineating the underlying mechanisms has been challenging. Here we show that manipulation of a single schizophrenia susceptibility gene, dysbindin...
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Veröffentlicht in: | Proceedings of the National Academy of Sciences - PNAS 2011-11, Vol.108 (46), p.18831-18836 |
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Sprache: | eng |
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