Rac and Cdc42 GTPases Control Hematopoietic Stem Cell Shape, Adhesion, Migration, and Mobilization

Critical to homeostasis of blood cell production by hematopoietic stem/progenitor (HSC/P) cells is the regulation of HSC/P retention within the bone marrow microenvironment and migration between the bone marrow and the blood. Key extracellular regulatory elements for this process have been defined (...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2001-05, Vol.98 (10), p.5614-5618
Hauptverfasser:	F.-C. Yang, Atkinson, S. J., Gu, Y., Borneo, J. B., Roberts, A. W., Zheng, Y., Pennington, J., Williams, D. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies Base Sequence Biological Sciences Blood Blood cells Bone marrow Bone marrow cells cdc42 GTP-Binding Protein - physiology Cell adhesion Cell Adhesion - physiology Cell lines Cell Movement - physiology Cell Size - physiology Cells Cellular biology DNA Primers Hematopoietic Stem Cells - cytology Mast cells Mice Mice, Inbred Strains rac GTP-Binding Proteins - physiology Stem cells
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