Distinct microRNA expression profiles in acute myeloid leukemia with common translocations

MicroRNAs (miRNAs) are postulated to be important regulators in cancers. Here, we report a genome-wide miRNA expression analysis in 52 acute myeloid leukemia (AML) samples with common translocations, including t(8;21)/AML1(RUNX1)-ETO(RUNX1T1), inv(16)/CBFB-MYH11, t(15;17)/PML-RARA, and MLL rearrange...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2008-10, Vol.105 (40), p.15535-15540
Hauptverfasser:	Li, Zejuan, Lu, Jun, Sun, Miao, Mi, Shuangli, Zhang, Hao, Luo, Roger T, Chen, Ping, Wang, Yungui, Yan, Ming, Qian, Zhijian, Neilly, Mary Beth, Jin, Jie, Zhang, Yanming, Bohlander, Stefan K, Zhang, Dong-Er, Larson, Richard A, Le Beau, Michelle M, Thirman, Michael J, Golub, Todd R, Rowley, Janet D, Chen, Jianjun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Biological Sciences Cell lines Cell Survival Core Binding Factors - genetics DNA Gene expression Gene Expression Profiling Genetic mutation Genetics Genomics Humans Kinases Leukemia Leukemia, Myeloid, Acute - genetics Methylation Mice MicroRNA MicroRNAs - metabolism Mutation Myeloid leukemia Protein-Serine-Threonine Kinases - metabolism Ribonucleic acid RNA Rodents Stem cells Translocation, Genetic
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!