NMDA Receptors Promote Survival in Somatosensory Relay Nuclei by Inhibiting Bax-Dependent Developmental Cell Death

Naturally occurring cell death is a universal feature of developing nervous systems that plays an essential role in determining adult brain function. Yet little is known about the decisions that select a subset of CNS neurons for survival and cause others to die. We report that postnatal day 0 NMDA...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2006-11, Vol.103 (45), p.16971-16976
Hauptverfasser:	de Rivero Vaccari, Juan Carlos, Casey, Gregory P., Aleem, Salman, Park, Won-Mee, Corriveau, Roderick A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antagonist drugs Apoptosis Apoptosis - physiology Base Sequence bcl-2-Associated X Protein - deficiency bcl-2-Associated X Protein - genetics bcl-2-Associated X Protein - physiology Biological Sciences Blood cells Brain Cell death Cell nucleus Cell Survival - physiology Death Dizocilpine Maleate - pharmacology DNA Primers - genetics Endothelial cells Female Knockout mice Mice Mice, Knockout N methyl D aspartate receptors Neurons Neuroscience Pregnancy Prenatal development Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors Receptors, N-Methyl-D-Aspartate - deficiency Receptors, N-Methyl-D-Aspartate - genetics Receptors, N-Methyl-D-Aspartate - physiology Somatosensory Cortex - cytology Somatosensory Cortex - drug effects Somatosensory Cortex - growth & development Somatosensory Cortex - physiology Trigeminal Nuclei - cytology Trigeminal Nuclei - drug effects Trigeminal Nuclei - growth & development Trigeminal Nuclei - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!