Endothelial selectin blockade attenuates lung permeability of experimental acid aspiration

Background: A central role for the polymorphonuclear leukocyte (PMN) in experimental acid aspiration has been demonstrated by the observation that PMN depletion reduced pulmonary vascular permeability. This study investigates the role of recombinant soluble P-selectin glycoprotein ligand-immunoglobu...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Surgery 2000-08, Vol.128 (2), p.327-331
Hauptverfasser:	Kyriakides, Constantinos, Austen, William, Wang, Yong, Favuzza, Joanne, Moore, Francis D., Hechtman, Herbert B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Capillary Permeability - drug effects Capillary Permeability - physiology E-Selectin - physiology Endothelium, Vascular - drug effects Endothelium, Vascular - physiology Hydrochloric Acid - administration & dosage Hydrochloric Acid - toxicity Inhalation Injuries of the thorax. Foreign bodies. Diseases due to physical agents Instillation, Drug Lung - drug effects Lung - pathology Lung - physiopathology Male Medical sciences Membrane Glycoproteins - pharmacology Mice Mice, Inbred C57BL Neutropenia - physiopathology Neutrophils - drug effects Neutrophils - physiology P-Selectin - physiology Pharmacology. Drug treatments Pulmonary Circulation - drug effects Pulmonary Circulation - physiology Recombinant Proteins - pharmacology Respiratory system Trachea Traumas. Diseases due to physical agents
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!