Massive OxyContin ingestion refractory to naloxone therapy
OxyContin (oxycodone hydrochloride controlled release) is a long-acting preparation of oxycodone that is used as an opioid analgesic to treat chronic pain conditions. We report a patient who ingested a massive quantity of OxyContin and had altered mental status, noncardiogenic pulmonary edema, and h...
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| Veröffentlicht in: | Annals of emergency medicine 2002-10, Vol.40 (4), p.425-428 |
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| container_end_page | 428 |
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| container_issue | 4 |
| container_start_page | 425 |
| container_title | Annals of emergency medicine |
| container_volume | 40 |
| creator | Schneir, Aaron B. Vadeboncoeur, Tyler F. Offerman, Steven R. Barry, James D. Ly, Binh T. Williams, Saralyn R. Clark, Richard F. |
| description | OxyContin (oxycodone hydrochloride controlled release) is a long-acting preparation of oxycodone that is used as an opioid analgesic to treat chronic pain conditions. We report a patient who ingested a massive quantity of OxyContin and had altered mental status, noncardiogenic pulmonary edema, and hypoventilation that proved refractory to naloxone administration. She required mechanical ventilation for 3 days before recovering completely. The severity and length of poisoning was likely related both to the quantity and formulation of the oxycodone ingested. [Ann Emerg Med. 2002;40:425-428.] |
| doi_str_mv | 10.1067/mem.2002.128143 |
| format | Article |
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We report a patient who ingested a massive quantity of OxyContin and had altered mental status, noncardiogenic pulmonary edema, and hypoventilation that proved refractory to naloxone administration. She required mechanical ventilation for 3 days before recovering completely. The severity and length of poisoning was likely related both to the quantity and formulation of the oxycodone ingested. [Ann Emerg Med. 2002;40:425-428.]</description><subject>Biological and medical sciences</subject><subject>Drug intoxications. Doping</subject><subject>Female</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Naloxone - therapeutic use</subject><subject>Narcotic Antagonists - therapeutic use</subject><subject>Narcotics - poisoning</subject><subject>Oxycodone - antagonists & inhibitors</subject><subject>Oxycodone - poisoning</subject><subject>Pharmacology. Drug treatments</subject><subject>Respiration, Artificial</subject><subject>Severity of Illness Index</subject><subject>Suicide, Attempted</subject><subject>Treatment Outcome</subject><issn>0196-0644</issn><issn>1097-6760</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kDtPwzAUhS0EoqUws6EsjGmvH7VjNlTxkoq6wGw5jg1GrVPZoWr-Pa5SqRPTXb5zdb6D0C2GKQYuZhu7mRIAMsWkwoyeoTEGKUouOJyjMWDJS-CMjdBVSj8AIBnBl2iECaFyDjBGD-86Jb-zxWrfL9rQ-VD48GVT59tQROuiNl0b-6Jri6DX7b4Ntui-bdTb_hpdOL1O9uZ4J-jz-elj8VouVy9vi8dlaSiFruTV3DkHFNt5jZsaY0eJNVw40VQVcZXAkoKmQjspOdecOSZYrU1NRDYkhk7QbPhrYptS7qS20W907BUGdVhB5RXUYQU1rJATd0Ni-1tvbHPij9oZuD8COhm9zpbB-HTiqOQCmMycHDib_XbeRpWMt8HYxkdrOtW0_t8Sf8xQeEY</recordid><startdate>20021001</startdate><enddate>20021001</enddate><creator>Schneir, Aaron B.</creator><creator>Vadeboncoeur, Tyler F.</creator><creator>Offerman, Steven R.</creator><creator>Barry, James D.</creator><creator>Ly, Binh T.</creator><creator>Williams, Saralyn R.</creator><creator>Clark, Richard F.</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20021001</creationdate><title>Massive OxyContin ingestion refractory to naloxone therapy</title><author>Schneir, Aaron B. ; Vadeboncoeur, Tyler F. ; Offerman, Steven R. ; Barry, James D. ; Ly, Binh T. ; Williams, Saralyn R. ; Clark, Richard F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c330t-685fff031e5b1db11f32ec67f7d882f871930a37af9966a64f474bacb270672c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Biological and medical sciences</topic><topic>Drug intoxications. 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| fulltext | fulltext |
| identifier | ISSN: 0196-0644 |
| ispartof | Annals of emergency medicine, 2002-10, Vol.40 (4), p.425-428 |
| issn | 0196-0644 1097-6760 |
| language | eng |
| recordid | cdi_crossref_primary_10_1067_mem_2002_128143 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Biological and medical sciences Drug intoxications. Doping Female Humans Medical sciences Middle Aged Naloxone - therapeutic use Narcotic Antagonists - therapeutic use Narcotics - poisoning Oxycodone - antagonists & inhibitors Oxycodone - poisoning Pharmacology. Drug treatments Respiration, Artificial Severity of Illness Index Suicide, Attempted Treatment Outcome |
| title | Massive OxyContin ingestion refractory to naloxone therapy |
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