Airway compromise secondary to lingual hematoma complicating administration of tissue plasminogen activator for acute ischemic stroke

Hemorrhagic complications of tissue plasminogen activator (tPA) are well known. We report a case of a lingual hematoma that developed after tPA administration for an acute ischemic stroke that necessitated orotracheal intubation to maintain the patient's airway. This case demonstrates the need...

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Veröffentlicht in:Annals of emergency medicine 2001-10, Vol.38 (4), p.447-449
Hauptverfasser: Shaps, Howard J., Snyder, Graham E., Sama, Andrew E., Rudolph, Gary S.
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container_end_page 449
container_issue 4
container_start_page 447
container_title Annals of emergency medicine
container_volume 38
creator Shaps, Howard J.
Snyder, Graham E.
Sama, Andrew E.
Rudolph, Gary S.
description Hemorrhagic complications of tissue plasminogen activator (tPA) are well known. We report a case of a lingual hematoma that developed after tPA administration for an acute ischemic stroke that necessitated orotracheal intubation to maintain the patient's airway. This case demonstrates the need for thorough preadministration physical examination, as well as careful monitoring during infusion and after administration of this potent therapeutic agent. [Shaps HJ, Snyder GE, Sama AE, Rudolph GS. Airway compromise secondary to lingual hematoma complicating administration of tissue plasminogen activator for acute ischemic stroke. Ann Emerg Med. October 2001;38:447-449.]
doi_str_mv 10.1067/mem.2001.116615
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subjects Aged
Airway Obstruction - etiology
Airway Obstruction - therapy
Biological and medical sciences
Brain Ischemia
Drug toxicity and drugs side effects treatment
Female
Follow-Up Studies
Hematoma - chemically induced
Hematoma - complications
Humans
Intubation, Intratracheal
Medical sciences
Pharmacology. Drug treatments
Respiration, Artificial
Risk Assessment
Stroke - diagnosis
Stroke - drug therapy
Tissue Plasminogen Activator - adverse effects
Tissue Plasminogen Activator - therapeutic use
Tongue Diseases - chemically induced
Tongue Diseases - complications
Toxicity: blood
title Airway compromise secondary to lingual hematoma complicating administration of tissue plasminogen activator for acute ischemic stroke
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