Phase-sensitive swept source optical coherence tomography for imaging and quantifying of microbubbles in clear and scattering media
A phase resolved system based on swept source optical coherence tomography (SSOCT) called as phase-sensitive SSOCT to detect and quantify gas microbubbles in aqueous and tissue simulated media is developed. The structural images of gas microbubbles are obtained using conventional SSOCT, while common...
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| Veröffentlicht in: | Journal of applied physics 2009-05, Vol.105 (10), p.102040-102040-10 |
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| container_issue | 10 |
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| container_title | Journal of applied physics |
| container_volume | 105 |
| creator | Manapuram, Ravi Kiran Manne, Venu Gopal Reddy Larin, Kirill V. |
| description | A phase resolved system based on swept source optical coherence tomography (SSOCT) called as phase-sensitive SSOCT to detect and quantify gas microbubbles in aqueous and tissue simulated media is developed. The structural images of gas microbubbles are obtained using conventional SSOCT, while common path SSOCT was used to perform the phase-sensitive measurements. The system shows an axial resolution of
10
μ
m
, a phase sensitivity of
0.03
rad
, an imaging depth of up to
6
mm
in air, and a scanning speed of
20
kHz
for a single
A
-line. The structural images of the bubbles show an accuracy of
10
μ
m
, whereas the temporal phase response show an accuracy of
0.01
μ
m
. Images of rapidly moving bubbles are also presented which indicate that the SSOCT could be ultimately applied for the rapid assessment of microbubbles in biofluids and tissues. |
| doi_str_mv | 10.1063/1.3116614 |
| format | Article |
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10
μ
m
, a phase sensitivity of
0.03
rad
, an imaging depth of up to
6
mm
in air, and a scanning speed of
20
kHz
for a single
A
-line. The structural images of the bubbles show an accuracy of
10
μ
m
, whereas the temporal phase response show an accuracy of
0.01
μ
m
. Images of rapidly moving bubbles are also presented which indicate that the SSOCT could be ultimately applied for the rapid assessment of microbubbles in biofluids and tissues.</description><identifier>ISSN: 0021-8979</identifier><identifier>EISSN: 1089-7550</identifier><identifier>DOI: 10.1063/1.3116614</identifier><identifier>CODEN: JAPIAU</identifier><language>eng</language><publisher>American Institute of Physics</publisher><ispartof>Journal of applied physics, 2009-05, Vol.105 (10), p.102040-102040-10</ispartof><rights>2009 American Institute of Physics</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c284t-cd5a651abf52cbb1a5238cf98f632c7289cc12aaa51bd8105c1c0457c3cb5603</citedby><cites>FETCH-LOGICAL-c284t-cd5a651abf52cbb1a5238cf98f632c7289cc12aaa51bd8105c1c0457c3cb5603</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://pubs.aip.org/jap/article-lookup/doi/10.1063/1.3116614$$EHTML$$P50$$Gscitation$$H</linktohtml><link.rule.ids>314,776,780,790,1553,4497,27903,27904,76131,76137</link.rule.ids></links><search><creatorcontrib>Manapuram, Ravi Kiran</creatorcontrib><creatorcontrib>Manne, Venu Gopal Reddy</creatorcontrib><creatorcontrib>Larin, Kirill V.</creatorcontrib><title>Phase-sensitive swept source optical coherence tomography for imaging and quantifying of microbubbles in clear and scattering media</title><title>Journal of applied physics</title><description>A phase resolved system based on swept source optical coherence tomography (SSOCT) called as phase-sensitive SSOCT to detect and quantify gas microbubbles in aqueous and tissue simulated media is developed. The structural images of gas microbubbles are obtained using conventional SSOCT, while common path SSOCT was used to perform the phase-sensitive measurements. The system shows an axial resolution of
10
μ
m
, a phase sensitivity of
0.03
rad
, an imaging depth of up to
6
mm
in air, and a scanning speed of
20
kHz
for a single
A
-line. The structural images of the bubbles show an accuracy of
10
μ
m
, whereas the temporal phase response show an accuracy of
0.01
μ
m
. Images of rapidly moving bubbles are also presented which indicate that the SSOCT could be ultimately applied for the rapid assessment of microbubbles in biofluids and tissues.</description><issn>0021-8979</issn><issn>1089-7550</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><recordid>eNp1kEtLAzEUhYMoWKsL_0G2LkZzZ5p5bAQpvqCgi-6HmztJG5mZ1CRVuvaPO9MWd64O9_BxOXyMXYO4BZFnd3CbAeQ5zE7YBERZJYWU4pRNhEghKauiOmcXIXwIAVBm1YT9vK8x6CToPthovzQP33oTeXBbT5q7TbSELSe31l73QxNd51YeN-sdN85z2-HK9iuOfcM_t9hHa3bj7QzvLHmntkq1OnDbc2o1-j0YCGPUfuQ63Vi8ZGcG26Cvjjlly6fH5fwlWbw9v84fFgml5Swm1EjMJaAyMiWlAGWalWSq0uRZSkVaVkSQIqIE1ZQgJAGJmSwoIyVzkU3ZzeHtsCsEr0298cN-v6tB1KO8GuqjvIG9P7CBbMRoXf8_vDdY_xmsR4PZL7-Neq0</recordid><startdate>20090515</startdate><enddate>20090515</enddate><creator>Manapuram, Ravi Kiran</creator><creator>Manne, Venu Gopal Reddy</creator><creator>Larin, Kirill V.</creator><general>American Institute of Physics</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20090515</creationdate><title>Phase-sensitive swept source optical coherence tomography for imaging and quantifying of microbubbles in clear and scattering media</title><author>Manapuram, Ravi Kiran ; Manne, Venu Gopal Reddy ; Larin, Kirill V.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c284t-cd5a651abf52cbb1a5238cf98f632c7289cc12aaa51bd8105c1c0457c3cb5603</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Manapuram, Ravi Kiran</creatorcontrib><creatorcontrib>Manne, Venu Gopal Reddy</creatorcontrib><creatorcontrib>Larin, Kirill V.</creatorcontrib><collection>CrossRef</collection><jtitle>Journal of applied physics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Manapuram, Ravi Kiran</au><au>Manne, Venu Gopal Reddy</au><au>Larin, Kirill V.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Phase-sensitive swept source optical coherence tomography for imaging and quantifying of microbubbles in clear and scattering media</atitle><jtitle>Journal of applied physics</jtitle><date>2009-05-15</date><risdate>2009</risdate><volume>105</volume><issue>10</issue><spage>102040</spage><epage>102040-10</epage><pages>102040-102040-10</pages><issn>0021-8979</issn><eissn>1089-7550</eissn><coden>JAPIAU</coden><abstract>A phase resolved system based on swept source optical coherence tomography (SSOCT) called as phase-sensitive SSOCT to detect and quantify gas microbubbles in aqueous and tissue simulated media is developed. The structural images of gas microbubbles are obtained using conventional SSOCT, while common path SSOCT was used to perform the phase-sensitive measurements. The system shows an axial resolution of
10
μ
m
, a phase sensitivity of
0.03
rad
, an imaging depth of up to
6
mm
in air, and a scanning speed of
20
kHz
for a single
A
-line. The structural images of the bubbles show an accuracy of
10
μ
m
, whereas the temporal phase response show an accuracy of
0.01
μ
m
. Images of rapidly moving bubbles are also presented which indicate that the SSOCT could be ultimately applied for the rapid assessment of microbubbles in biofluids and tissues.</abstract><pub>American Institute of Physics</pub><doi>10.1063/1.3116614</doi></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0021-8979 |
| ispartof | Journal of applied physics, 2009-05, Vol.105 (10), p.102040-102040-10 |
| issn | 0021-8979 1089-7550 |
| language | eng |
| recordid | cdi_crossref_primary_10_1063_1_3116614 |
| source | AIP Journals Complete; AIP Digital Archive; Alma/SFX Local Collection |
| title | Phase-sensitive swept source optical coherence tomography for imaging and quantifying of microbubbles in clear and scattering media |
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