Single-molecule detection in a liquid by surface-enhanced resonance Raman scattering

Single-molecule detection in a liquid by surface-enhanced resonance Raman scattering

Surface-enhanced resonance Raman scattering (SERRS) of Rhodamine 6G (R6G) adsorbed on colloidal silver clusters in a liquid has been studied. The first observation of single molecule resonance Raman scattering in a liquid in a probed volume of 10 pL was achieved. Anisotropy of SERRS spectra of singl...

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Veröffentlicht in:Applied physics letters 2006-01, Vol.88 (3), p.034104-034104-3
Hauptverfasser: Zhou, Zenghui, Wang, Guiying, Xu, Zhizhan
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creator Zhou, Zenghui
Wang, Guiying
Xu, Zhizhan
description Surface-enhanced resonance Raman scattering (SERRS) of Rhodamine 6G (R6G) adsorbed on colloidal silver clusters in a liquid has been studied. The first observation of single molecule resonance Raman scattering in a liquid in a probed volume of 10 pL was achieved. Anisotropy of SERRS spectra of single R6G molecule and huge SERRS spectra were observed and compared with that of single molecule fixed in the dried films of sols, which revealed the intricate complex interaction between R6G molecules and the environment in a liquid.
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title Single-molecule detection in a liquid by surface-enhanced resonance Raman scattering
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