Sedimentation Coefficients of Linear and Cyclic Wormlike Coils with Excluded-Volume Effects

Sedimentation Coefficients of Linear and Cyclic Wormlike Coils with Excluded-Volume Effects

The sedimentation coefficient for the Kratky—Porod wormlike coil is calculated with the effects of excluded volume taken into account. The statistical length of native DNA is found to be 900 Å. The hydrodynamic diameter of the Watson—Crick helix is 26–27 Å. Sedimentation coefficients are calculated...

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Veröffentlicht in:The Journal of chemical physics 1967-01, Vol.46 (4), p.1493-1498
Hauptverfasser: Gray, Horace B., Bloomfield, Victor A., Hearst, John E.
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container_issue 4
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container_title The Journal of chemical physics
container_volume 46
creator Gray, Horace B.
Bloomfield, Victor A.
Hearst, John E.
description The sedimentation coefficient for the Kratky—Porod wormlike coil is calculated with the effects of excluded volume taken into account. The statistical length of native DNA is found to be 900 Å. The hydrodynamic diameter of the Watson—Crick helix is 26–27 Å. Sedimentation coefficients are calculated to decrease by about 13% on going from a cyclic native DNA to a linear molecule of the same molecular weight.
doi_str_mv 10.1063/1.1840879
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title Sedimentation Coefficients of Linear and Cyclic Wormlike Coils with Excluded-Volume Effects
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