Longitudinal Modeling of Age-Related Memory Decline and the APOE ε4 Effect

The APOE ε4 variant confers an increased risk of Alzheimer's disease. Longitudinal modeling of cognitive aging showed that memory decline in subjects with one or two APOE ε4 alleles diverged from that of noncarriers before the age of 60 years. The APOE ε4 variant confers an increased risk of Al...

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Veröffentlicht in:	The New England journal of medicine 2009-07, Vol.361 (3), p.255-263
Hauptverfasser:	Caselli, Richard J, Dueck, Amylou C, Osborne, David, Sabbagh, Marwan N, Connor, Donald J, Ahern, Geoffrey L, Baxter, Leslie C, Rapcsak, Steven Z, Shi, Jiong, Woodruff, Bryan K, Locke, Dona E.C, Snyder, Charlene Hoffman, Alexander, Gene E, Rademakers, Rosa, Reiman, Eric M
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences General aspects Medical sciences
Online-Zugang:	Volltext
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