Case 13-2014: A 41-Year-Old Man with Fever and Abdominal Pain after Stem-Cell Transplantation
A 41-year-old man with B-cell acute lymphoblastic leukemia underwent allogeneic peripheral-blood stem-cell transplantation; 12 days later, fever, abdominal pain, and peritoneal signs developed. Imaging showed acute retrocecal appendicitis and inflammation of the cecum. Presentation of Case Dr. Ricar...
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| Veröffentlicht in: | The New England journal of medicine 2014-04, Vol.370 (17), p.1637-1646 |
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| container_issue | 17 |
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| container_title | The New England journal of medicine |
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| creator | Kontoyiannis, Dimitrios P Mathur, Mahan Chen, Yi-Bin Shellito, Paul C Tse, Julie Y |
| description | A 41-year-old man with B-cell acute lymphoblastic leukemia underwent allogeneic peripheral-blood stem-cell transplantation; 12 days later, fever, abdominal pain, and peritoneal signs developed. Imaging showed acute retrocecal appendicitis and inflammation of the cecum.
Presentation of Case
Dr. Ricardo J. Cigarroa
(Medicine): A 41-year-old man with B-cell acute lymphoblastic leukemia (ALL) underwent allogeneic peripheral-blood stem-cell transplantation, and afterward, fever and abdominal pain developed.
The patient had been well until approximately 7 months before admission, when low-grade fevers and fatigue occurred; the fevers were associated with an unintentional weight loss of approximately 10 kg. Five months before admission, pain in his right arm and leg developed. Imaging performed at another hospital revealed deep venous thromboses, and analysis of a peripheral-blood smear revealed a white-cell count of 33,000 per cubic millimeter, with 53% blasts. Pathological examination . . . |
| doi_str_mv | 10.1056/NEJMcpc1305994 |
| format | Article |
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Presentation of Case
Dr. Ricardo J. Cigarroa
(Medicine): A 41-year-old man with B-cell acute lymphoblastic leukemia (ALL) underwent allogeneic peripheral-blood stem-cell transplantation, and afterward, fever and abdominal pain developed.
The patient had been well until approximately 7 months before admission, when low-grade fevers and fatigue occurred; the fevers were associated with an unintentional weight loss of approximately 10 kg. Five months before admission, pain in his right arm and leg developed. Imaging performed at another hospital revealed deep venous thromboses, and analysis of a peripheral-blood smear revealed a white-cell count of 33,000 per cubic millimeter, with 53% blasts. Pathological examination . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMcpc1305994</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>Waltham, MA: Massachusetts Medical Society</publisher><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Bone marrow, stem cells transplantation. Graft versus host reaction ; General aspects ; Medical sciences ; Transfusions. Complications. Transfusion reactions. Cell and gene therapy</subject><ispartof>The New England journal of medicine, 2014-04, Vol.370 (17), p.1637-1646</ispartof><rights>Copyright © 2014 Massachusetts Medical Society. All rights reserved.</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c255t-56c21d39726e46b31a84f4274ab86adfc495962efbc9ec3a89d812bc9bf8644d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMcpc1305994$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJMcpc1305994$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,780,784,2759,2760,26103,27924,27925,52382,54064</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=28434473$$DView record in Pascal Francis$$Hfree_for_read</backlink></links><search><contributor>Ebeling, Sally H</contributor><contributor>Cabot, Richard C</contributor><contributor>McDonald, Emily K</contributor><contributor>Rosenberg, Eric S</contributor><contributor>Harris, Nancy Lee</contributor><contributor>Shepard, Jo-Anne O</contributor><contributor>Cort, Alice M</contributor><contributor>Cort, Alice M.</contributor><contributor>Shepard, Jo-Anne O.</contributor><contributor>McDonald, Emily K.</contributor><contributor>Ebeling, Sally H.</contributor><contributor>Rosenberg, Eric S.</contributor><contributor>Cabot, Richard C.</contributor><creatorcontrib>Kontoyiannis, Dimitrios P</creatorcontrib><creatorcontrib>Mathur, Mahan</creatorcontrib><creatorcontrib>Chen, Yi-Bin</creatorcontrib><creatorcontrib>Shellito, Paul C</creatorcontrib><creatorcontrib>Tse, Julie Y</creatorcontrib><title>Case 13-2014: A 41-Year-Old Man with Fever and Abdominal Pain after Stem-Cell Transplantation</title><title>The New England journal of medicine</title><description>A 41-year-old man with B-cell acute lymphoblastic leukemia underwent allogeneic peripheral-blood stem-cell transplantation; 12 days later, fever, abdominal pain, and peritoneal signs developed. Imaging showed acute retrocecal appendicitis and inflammation of the cecum.
Presentation of Case
Dr. Ricardo J. Cigarroa
(Medicine): A 41-year-old man with B-cell acute lymphoblastic leukemia (ALL) underwent allogeneic peripheral-blood stem-cell transplantation, and afterward, fever and abdominal pain developed.
The patient had been well until approximately 7 months before admission, when low-grade fevers and fatigue occurred; the fevers were associated with an unintentional weight loss of approximately 10 kg. Five months before admission, pain in his right arm and leg developed. Imaging performed at another hospital revealed deep venous thromboses, and analysis of a peripheral-blood smear revealed a white-cell count of 33,000 per cubic millimeter, with 53% blasts. Pathological examination . . .</description><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Bone marrow, stem cells transplantation. Graft versus host reaction</subject><subject>General aspects</subject><subject>Medical sciences</subject><subject>Transfusions. Complications. Transfusion reactions. Cell and gene therapy</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNp1j0FLAzEUhIMouLZePXvRW9ok7yWbHGWpVWn1oueQfZtAS7cuGy_-eyMrggfnMgzMNzCMXUmxkEKb5fPqaUsDSRDaOTxhldQAHFGYU1YJoSzH2sE5u8h5L4okuorNm5DjtQSuSp6zsxQOOV7--Iy93a9emwe-eVk_NncbTkrrD64NKdmBq5WJaFqQwWJCVWNorQldInTaGRVTSy4SBOs6K1UJbbIGsYMZW0y7NL7nPMbkh3HXh_HTS-G_v_i_XwpwMwFDyBQOaQxH2uVfSlkExBpK73bq9X32x7jv_xv8AssdUeo</recordid><startdate>20140424</startdate><enddate>20140424</enddate><creator>Kontoyiannis, Dimitrios P</creator><creator>Mathur, Mahan</creator><creator>Chen, Yi-Bin</creator><creator>Shellito, Paul C</creator><creator>Tse, Julie Y</creator><general>Massachusetts Medical Society</general><scope>IQODW</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20140424</creationdate><title>Case 13-2014</title><author>Kontoyiannis, Dimitrios P ; Mathur, Mahan ; Chen, Yi-Bin ; Shellito, Paul C ; Tse, Julie Y</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c255t-56c21d39726e46b31a84f4274ab86adfc495962efbc9ec3a89d812bc9bf8644d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Bone marrow, stem cells transplantation. Graft versus host reaction</topic><topic>General aspects</topic><topic>Medical sciences</topic><topic>Transfusions. Complications. Transfusion reactions. Cell and gene therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kontoyiannis, Dimitrios P</creatorcontrib><creatorcontrib>Mathur, Mahan</creatorcontrib><creatorcontrib>Chen, Yi-Bin</creatorcontrib><creatorcontrib>Shellito, Paul C</creatorcontrib><creatorcontrib>Tse, Julie Y</creatorcontrib><collection>Pascal-Francis</collection><collection>CrossRef</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kontoyiannis, Dimitrios P</au><au>Mathur, Mahan</au><au>Chen, Yi-Bin</au><au>Shellito, Paul C</au><au>Tse, Julie Y</au><au>Ebeling, Sally H</au><au>Cabot, Richard C</au><au>McDonald, Emily K</au><au>Rosenberg, Eric S</au><au>Harris, Nancy Lee</au><au>Shepard, Jo-Anne O</au><au>Cort, Alice M</au><au>Cort, Alice M.</au><au>Shepard, Jo-Anne O.</au><au>McDonald, Emily K.</au><au>Ebeling, Sally H.</au><au>Rosenberg, Eric S.</au><au>Cabot, Richard C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Case 13-2014: A 41-Year-Old Man with Fever and Abdominal Pain after Stem-Cell Transplantation</atitle><jtitle>The New England journal of medicine</jtitle><date>2014-04-24</date><risdate>2014</risdate><volume>370</volume><issue>17</issue><spage>1637</spage><epage>1646</epage><pages>1637-1646</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><coden>NEJMAG</coden><abstract>A 41-year-old man with B-cell acute lymphoblastic leukemia underwent allogeneic peripheral-blood stem-cell transplantation; 12 days later, fever, abdominal pain, and peritoneal signs developed. Imaging showed acute retrocecal appendicitis and inflammation of the cecum.
Presentation of Case
Dr. Ricardo J. Cigarroa
(Medicine): A 41-year-old man with B-cell acute lymphoblastic leukemia (ALL) underwent allogeneic peripheral-blood stem-cell transplantation, and afterward, fever and abdominal pain developed.
The patient had been well until approximately 7 months before admission, when low-grade fevers and fatigue occurred; the fevers were associated with an unintentional weight loss of approximately 10 kg. Five months before admission, pain in his right arm and leg developed. Imaging performed at another hospital revealed deep venous thromboses, and analysis of a peripheral-blood smear revealed a white-cell count of 33,000 per cubic millimeter, with 53% blasts. Pathological examination . . .</abstract><cop>Waltham, MA</cop><pub>Massachusetts Medical Society</pub><doi>10.1056/NEJMcpc1305994</doi><tpages>10</tpages></addata></record> |
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| source | New England Journal of Medicine Current; EZB-FREE-00999 freely available EZB journals; ProQuest Central UK/Ireland |
| subjects | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Bone marrow, stem cells transplantation. Graft versus host reaction General aspects Medical sciences Transfusions. Complications. Transfusion reactions. Cell and gene therapy |
| title | Case 13-2014: A 41-Year-Old Man with Fever and Abdominal Pain after Stem-Cell Transplantation |
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