Lactic Acidosis in Patients with Diabetes Treated with Metformin

To the Editor: From May 1995, when metformin was introduced in the United States, through June 30, 1996, the Food and Drug Administration (FDA) received reports of lactic acidosis in 66 patients treated with metformin. In 47 patients, the diagnosis was confirmed on the basis of circulating lactate v...

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Veröffentlicht in:	The New England journal of medicine 1998-01, Vol.338 (4), p.265-266
Hauptverfasser:	Misbin, Robert I, Green, Lanh, Stadel, Bruce V, Gueriguian, John L, Gubbi, Ananda, Fleming, G. Alexander
Format:	Artikel
Sprache:	eng
Schlagworte:	Acidosis, Lactic - chemically induced Aged Diabetes Mellitus - drug therapy Female Humans Hypoglycemic Agents - adverse effects Male Metformin - adverse effects Risk Factors
Online-Zugang:	Volltext
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