Kinetic Resolution of Pyridyl Alcohols by Cu(II)(Borabox)-Catalyzed Acylation
Abstract Kinetic resolution of pyridyl alcohols has been achieved using copper(II)(borabox)-catalyzed benzoylation. Selectivity factors (k rel ) of up to 125 have been observed and application to the synthesis of chiral pyridyl phosphine ligands is described.
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| Veröffentlicht in: | Synthesis (Stuttgart) 2007-12, Vol.2007 (23), p.3751-3753 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | Abstract
Kinetic resolution of pyridyl alcohols has been achieved using copper(II)(borabox)-catalyzed benzoylation. Selectivity factors (k
rel
) of up to 125 have been observed and application to the synthesis of chiral pyridyl phosphine ligands is described. |
|---|---|
| ISSN: | 0039-7881 1437-210X |
| DOI: | 10.1055/s-2007-983850 |