Protective Effect of Gamma-Hydroxybutyrate and Nicotinamide on Low-Dose Streptozotocin-Induced Diabetes in Mice

Abstract The purpose of this study was to investigate the effect of a treatment by gamma-hydroxybutyrate (GHB) and nicotinamide (NA) on low-dose streptozotocin (STZ)-induced diabetes in mice. Mean plasma glucose level was significantly elevated in mice given STZ by day 12 after the first STZ injecti...

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Veröffentlicht in:	Hormone and metabolic research 1995-05, Vol.27 (5), p.216-220
Hauptverfasser:	Bouix, O., Reynier, M., Guintrand-Hugret, R., Orsetti, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Glucose - analysis Diabetes Mellitus, Experimental - prevention & control Drug Synergism Insulin - metabolism Insulin Secretion Islets of Langerhans - drug effects Islets of Langerhans - metabolism Male Mice Niacinamide - pharmacology Originals Basic Rats Rats, Wistar Sodium Oxybate - pharmacology Streptozocin
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