Effects of Comedication on the Serum Levels of Aripiprazole: Evidence from a Routine Therapeutic Drug Monitoring Service

Abstract INTRODUCTION: The objective of the study was to compare the serum concentrations of the atypical antipsychotic aripiprazole in monotherapy with the concentrations found during concomitant therapy with other drugs. METHODS: Samples analyzed for aripiprazole by a liquid chromatography-mass sp...

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Veröffentlicht in:	Pharmacopsychiatry 2007-05, Vol.40 (3), p.107-110
Hauptverfasser:	Castberg, I., Spigset, O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antimanic Agents - administration & dosage Antimanic Agents - pharmacology Antipsychotic Agents - administration & dosage Antipsychotic Agents - blood Antipsychotic Agents - pharmacokinetics Aripiprazole Carbamazepine - administration & dosage Carbamazepine - pharmacology Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP3A Cytochrome P-450 Enzyme System - biosynthesis Drug Interactions Drug Monitoring Drug Therapy, Combination Enzyme Induction Female Humans Male Middle Aged Original Paper Piperazines - administration & dosage Piperazines - blood Piperazines - pharmacokinetics Quinolones - administration & dosage Quinolones - blood Quinolones - pharmacokinetics Valproic Acid - pharmacology
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