Numerical simulation of pulsatile blood flow in the human left ventricle
Objective: On behalf of computational fluid dynamics intracardiac flow shall be simulated to identify flow patterns and resulting energy loss with respect to different ventricular geometries. Methods: After acquisition of individual MRI-data, time-related geometry of the left heart chambers is gener...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , |
|---|---|
| Format: | Tagungsbericht |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | S 1 |
| container_start_page | |
| container_title | |
| container_volume | 55 |
| creator | Schiller, W Spiegel, K Schmid, T Rudorf, H Flacke, S Probst, C Kovacz, A Schenkel, T Welz, A Oertel, H Liepsch, D |
| description | Objective:
On behalf of computational fluid dynamics intracardiac flow shall be simulated to identify flow patterns and resulting energy loss with respect to different ventricular geometries.
Methods:
After acquisition of individual MRI-data, time-related geometry of the left heart chambers is generated by segmentation, post-processing and modelling. The coupling to a simplified model of planar heart valves with spatially varying resistance and a preformed aorta completes the numeric flow model. Physiological boundary conditions such as pre- and afterload are given by a simplified circulation model. A validation experiment is performed using a silicone ventricle created on basis of the same MRI data. In the experimental setup flow patterns are described with laser doppler measurements. Methodical influences are revealed by comparing the numerical simulation with MRI-flow measurements.
Results:
The developed method of simulating intracardiac blood flow gives a new fundament to understand the impact of different ventricular geometries respectively pathomorphologies on intraventricular blood flow. It is for the first time possible to simulate the asymmetric redirection in the left atrium and ventricle as described on the basis of MRI flow measurements.
Conclusion:
In contrast to medical flow imaging numerical simulation enables us to perform intraventricular energy estimations. Future aspects comprise a therapy planning system enabling us to compare different therapeutic strategies influencing the ventricular geometry. |
| doi_str_mv | 10.1055/s-2007-967594 |
| format | Conference Proceeding |
| fullrecord | <record><control><sourceid>thieme_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1055_s_2007_967594</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>10_1055_s_2007_967594</sourcerecordid><originalsourceid>FETCH-LOGICAL-c754-c6b0aff0c59e7d4f88be852757be68d66243c0cb525b9c551b082baa06f09ba03</originalsourceid><addsrcrecordid>eNp1kE1LAzEURYMoWKtL9_kBRl8y-VxKUSsU3XQfkjShUzKTMplR_PdOqVtXjwvnXh4HoXsKjxSEeKqEAShipBKGX6AF5Y0h1AC7RAugihLJmbhGN7UeACjX2izQ-mPq4tAGl3Ftuym7sS09Lgkfp1znkCP2uZQdTrl847bH4z7i_dS5HueYRvwV-3Gu53iLrpLLNd793SXavr5sV2uy-Xx7Xz1vSFCCkyA9uJQgCBPVjietfdSCKaF8lHonJeNNgOAFE94EIagHzbxzIBMY76BZInKeDUOpdYjJHoe2c8OPpWBPFmy1Jwv2bGHmH878uG9jF-2hTEM___cP_gtplF5J</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>conference_proceeding</recordtype></control><display><type>conference_proceeding</type><title>Numerical simulation of pulsatile blood flow in the human left ventricle</title><source>Thieme Connect Journals</source><creator>Schiller, W ; Spiegel, K ; Schmid, T ; Rudorf, H ; Flacke, S ; Probst, C ; Kovacz, A ; Schenkel, T ; Welz, A ; Oertel, H ; Liepsch, D</creator><creatorcontrib>Schiller, W ; Spiegel, K ; Schmid, T ; Rudorf, H ; Flacke, S ; Probst, C ; Kovacz, A ; Schenkel, T ; Welz, A ; Oertel, H ; Liepsch, D</creatorcontrib><description>Objective:
On behalf of computational fluid dynamics intracardiac flow shall be simulated to identify flow patterns and resulting energy loss with respect to different ventricular geometries.
Methods:
After acquisition of individual MRI-data, time-related geometry of the left heart chambers is generated by segmentation, post-processing and modelling. The coupling to a simplified model of planar heart valves with spatially varying resistance and a preformed aorta completes the numeric flow model. Physiological boundary conditions such as pre- and afterload are given by a simplified circulation model. A validation experiment is performed using a silicone ventricle created on basis of the same MRI data. In the experimental setup flow patterns are described with laser doppler measurements. Methodical influences are revealed by comparing the numerical simulation with MRI-flow measurements.
Results:
The developed method of simulating intracardiac blood flow gives a new fundament to understand the impact of different ventricular geometries respectively pathomorphologies on intraventricular blood flow. It is for the first time possible to simulate the asymmetric redirection in the left atrium and ventricle as described on the basis of MRI flow measurements.
Conclusion:
In contrast to medical flow imaging numerical simulation enables us to perform intraventricular energy estimations. Future aspects comprise a therapy planning system enabling us to compare different therapeutic strategies influencing the ventricular geometry.</description><identifier>ISSN: 0171-6425</identifier><identifier>EISSN: 1439-1902</identifier><identifier>DOI: 10.1055/s-2007-967594</identifier><language>eng</language><ispartof>The Thoracic and cardiovascular surgeon, 2007, Vol.55 (S 1)</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>309,310,314,776,780,785,786,3004,3005,23909,23910,25118,27901,27902</link.rule.ids></links><search><creatorcontrib>Schiller, W</creatorcontrib><creatorcontrib>Spiegel, K</creatorcontrib><creatorcontrib>Schmid, T</creatorcontrib><creatorcontrib>Rudorf, H</creatorcontrib><creatorcontrib>Flacke, S</creatorcontrib><creatorcontrib>Probst, C</creatorcontrib><creatorcontrib>Kovacz, A</creatorcontrib><creatorcontrib>Schenkel, T</creatorcontrib><creatorcontrib>Welz, A</creatorcontrib><creatorcontrib>Oertel, H</creatorcontrib><creatorcontrib>Liepsch, D</creatorcontrib><title>Numerical simulation of pulsatile blood flow in the human left ventricle</title><title>The Thoracic and cardiovascular surgeon</title><addtitle>Thorac cardiovasc Surg</addtitle><description>Objective:
On behalf of computational fluid dynamics intracardiac flow shall be simulated to identify flow patterns and resulting energy loss with respect to different ventricular geometries.
Methods:
After acquisition of individual MRI-data, time-related geometry of the left heart chambers is generated by segmentation, post-processing and modelling. The coupling to a simplified model of planar heart valves with spatially varying resistance and a preformed aorta completes the numeric flow model. Physiological boundary conditions such as pre- and afterload are given by a simplified circulation model. A validation experiment is performed using a silicone ventricle created on basis of the same MRI data. In the experimental setup flow patterns are described with laser doppler measurements. Methodical influences are revealed by comparing the numerical simulation with MRI-flow measurements.
Results:
The developed method of simulating intracardiac blood flow gives a new fundament to understand the impact of different ventricular geometries respectively pathomorphologies on intraventricular blood flow. It is for the first time possible to simulate the asymmetric redirection in the left atrium and ventricle as described on the basis of MRI flow measurements.
Conclusion:
In contrast to medical flow imaging numerical simulation enables us to perform intraventricular energy estimations. Future aspects comprise a therapy planning system enabling us to compare different therapeutic strategies influencing the ventricular geometry.</description><issn>0171-6425</issn><issn>1439-1902</issn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2007</creationdate><recordtype>conference_proceeding</recordtype><sourceid>0U6</sourceid><recordid>eNp1kE1LAzEURYMoWKtL9_kBRl8y-VxKUSsU3XQfkjShUzKTMplR_PdOqVtXjwvnXh4HoXsKjxSEeKqEAShipBKGX6AF5Y0h1AC7RAugihLJmbhGN7UeACjX2izQ-mPq4tAGl3Ftuym7sS09Lgkfp1znkCP2uZQdTrl847bH4z7i_dS5HueYRvwV-3Gu53iLrpLLNd793SXavr5sV2uy-Xx7Xz1vSFCCkyA9uJQgCBPVjietfdSCKaF8lHonJeNNgOAFE94EIagHzbxzIBMY76BZInKeDUOpdYjJHoe2c8OPpWBPFmy1Jwv2bGHmH878uG9jF-2hTEM___cP_gtplF5J</recordid><startdate>20070327</startdate><enddate>20070327</enddate><creator>Schiller, W</creator><creator>Spiegel, K</creator><creator>Schmid, T</creator><creator>Rudorf, H</creator><creator>Flacke, S</creator><creator>Probst, C</creator><creator>Kovacz, A</creator><creator>Schenkel, T</creator><creator>Welz, A</creator><creator>Oertel, H</creator><creator>Liepsch, D</creator><scope>0U6</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20070327</creationdate><title>Numerical simulation of pulsatile blood flow in the human left ventricle</title><author>Schiller, W ; Spiegel, K ; Schmid, T ; Rudorf, H ; Flacke, S ; Probst, C ; Kovacz, A ; Schenkel, T ; Welz, A ; Oertel, H ; Liepsch, D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c754-c6b0aff0c59e7d4f88be852757be68d66243c0cb525b9c551b082baa06f09ba03</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2007</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schiller, W</creatorcontrib><creatorcontrib>Spiegel, K</creatorcontrib><creatorcontrib>Schmid, T</creatorcontrib><creatorcontrib>Rudorf, H</creatorcontrib><creatorcontrib>Flacke, S</creatorcontrib><creatorcontrib>Probst, C</creatorcontrib><creatorcontrib>Kovacz, A</creatorcontrib><creatorcontrib>Schenkel, T</creatorcontrib><creatorcontrib>Welz, A</creatorcontrib><creatorcontrib>Oertel, H</creatorcontrib><creatorcontrib>Liepsch, D</creatorcontrib><collection>Thieme Connect Journals Open Access</collection><collection>CrossRef</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schiller, W</au><au>Spiegel, K</au><au>Schmid, T</au><au>Rudorf, H</au><au>Flacke, S</au><au>Probst, C</au><au>Kovacz, A</au><au>Schenkel, T</au><au>Welz, A</au><au>Oertel, H</au><au>Liepsch, D</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>Numerical simulation of pulsatile blood flow in the human left ventricle</atitle><btitle>The Thoracic and cardiovascular surgeon</btitle><addtitle>Thorac cardiovasc Surg</addtitle><date>2007-03-27</date><risdate>2007</risdate><volume>55</volume><issue>S 1</issue><issn>0171-6425</issn><eissn>1439-1902</eissn><abstract>Objective:
On behalf of computational fluid dynamics intracardiac flow shall be simulated to identify flow patterns and resulting energy loss with respect to different ventricular geometries.
Methods:
After acquisition of individual MRI-data, time-related geometry of the left heart chambers is generated by segmentation, post-processing and modelling. The coupling to a simplified model of planar heart valves with spatially varying resistance and a preformed aorta completes the numeric flow model. Physiological boundary conditions such as pre- and afterload are given by a simplified circulation model. A validation experiment is performed using a silicone ventricle created on basis of the same MRI data. In the experimental setup flow patterns are described with laser doppler measurements. Methodical influences are revealed by comparing the numerical simulation with MRI-flow measurements.
Results:
The developed method of simulating intracardiac blood flow gives a new fundament to understand the impact of different ventricular geometries respectively pathomorphologies on intraventricular blood flow. It is for the first time possible to simulate the asymmetric redirection in the left atrium and ventricle as described on the basis of MRI flow measurements.
Conclusion:
In contrast to medical flow imaging numerical simulation enables us to perform intraventricular energy estimations. Future aspects comprise a therapy planning system enabling us to compare different therapeutic strategies influencing the ventricular geometry.</abstract><doi>10.1055/s-2007-967594</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0171-6425 |
| ispartof | The Thoracic and cardiovascular surgeon, 2007, Vol.55 (S 1) |
| issn | 0171-6425 1439-1902 |
| language | eng |
| recordid | cdi_crossref_primary_10_1055_s_2007_967594 |
| source | Thieme Connect Journals |
| title | Numerical simulation of pulsatile blood flow in the human left ventricle |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-21T17%3A14%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-thieme_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=proceeding&rft.atitle=Numerical%20simulation%20of%20pulsatile%20blood%20flow%20in%20the%20human%20left%20ventricle&rft.btitle=The%20Thoracic%20and%20cardiovascular%20surgeon&rft.au=Schiller,%20W&rft.date=2007-03-27&rft.volume=55&rft.issue=S%201&rft.issn=0171-6425&rft.eissn=1439-1902&rft_id=info:doi/10.1055/s-2007-967594&rft_dat=%3Cthieme_cross%3E10_1055_s_2007_967594%3C/thieme_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |