Replacement of aprotinin by tranexamic acid during on-pump cardiac surgery: A retrospective evaluation of clinical outcome and cost-effectiveness
Aims: The antifibrinolytics aprotinin and tranexamic acid (TXA) are established blood saving agents in surgical treatment including cardiac surgery. Methods: Because of the anticipated better risk/benefit ratio of TXA the established antifibrinolytic treatment with aprotinin was replaced by a TXA tr...
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