Molluscicidal Constituents of Calophyllum from Madagascar: Activity of Some Natural and Synthetic Neoflavonoids and Khellactones
Abstract Crude extracts of seeds, leaves and barks of four Madagascan CALOPHYLLUM species: C. INOPHYLLUM, C. RECEDENS, C. CHAPELIERI, and C. VERTICILLATUM, have been tested for molluscicidal activity against BIOMPHALARIA GLABRATA. All seed extracts showed significant activity. The major constituents...
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| Veröffentlicht in: | Planta medica 1992-02, Vol.58 (1), p.51-55 |
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| container_title | Planta medica |
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| creator | Ravelonjato, Bernard Libot, Francine Ramiandrasoa, Florence Kunesch, Nicole Gayral, Philippe Poisson, Jacques |
| description | Abstract
Crude extracts of seeds, leaves and barks of four Madagascan CALOPHYLLUM species: C. INOPHYLLUM, C. RECEDENS, C. CHAPELIERI, and C. VERTICILLATUM, have been tested for molluscicidal activity against BIOMPHALARIA GLABRATA. All seed extracts showed significant activity. The major constituents of the most active CALOPHYLLUM species were examinated. Some related coumarinic derivatives were synthesized in order to improve the biological activity. Among the compounds prepared, 5,7-dihydroxy-6-(2-methylbutyryl)-4-phenylcoumarin presented an interesting molluscicidal activity. |
| doi_str_mv | 10.1055/s-2006-961389 |
| format | Article |
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Crude extracts of seeds, leaves and barks of four Madagascan CALOPHYLLUM species: C. INOPHYLLUM, C. RECEDENS, C. CHAPELIERI, and C. VERTICILLATUM, have been tested for molluscicidal activity against BIOMPHALARIA GLABRATA. All seed extracts showed significant activity. The major constituents of the most active CALOPHYLLUM species were examinated. Some related coumarinic derivatives were synthesized in order to improve the biological activity. Among the compounds prepared, 5,7-dihydroxy-6-(2-methylbutyryl)-4-phenylcoumarin presented an interesting molluscicidal activity.</description><identifier>ISSN: 0032-0943</identifier><identifier>EISSN: 1439-0221</identifier><identifier>DOI: 10.1055/s-2006-961389</identifier><identifier>PMID: 1620744</identifier><language>eng</language><publisher>Germany</publisher><subject>Animals ; Biomphalaria - drug effects ; Flavonoids - chemical synthesis ; Flavonoids - isolation & purification ; Flavonoids - pharmacology ; Lactones - chemical synthesis ; Lactones - isolation & purification ; Lactones - pharmacology ; Madagascar ; Molluscacides - chemical synthesis ; Molluscacides - isolation & purification ; Molluscacides - pharmacology ; Plants - chemistry</subject><ispartof>Planta medica, 1992-02, Vol.58 (1), p.51-55</ispartof><rights>Georg Thieme Verlag Stuttgart · New York</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c325t-5a6d6fc87137a309302dc61c753c042250e6d8c2fdb853bc335e26f374146dc93</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2006-961389.pdf$$EPDF$$P50$$Gthieme$$H</linktopdf><link.rule.ids>314,780,784,3017,3018,27924,27925,54559</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1620744$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ravelonjato, Bernard</creatorcontrib><creatorcontrib>Libot, Francine</creatorcontrib><creatorcontrib>Ramiandrasoa, Florence</creatorcontrib><creatorcontrib>Kunesch, Nicole</creatorcontrib><creatorcontrib>Gayral, Philippe</creatorcontrib><creatorcontrib>Poisson, Jacques</creatorcontrib><title>Molluscicidal Constituents of Calophyllum from Madagascar: Activity of Some Natural and Synthetic Neoflavonoids and Khellactones</title><title>Planta medica</title><addtitle>Planta Med</addtitle><description>Abstract
Crude extracts of seeds, leaves and barks of four Madagascan CALOPHYLLUM species: C. INOPHYLLUM, C. RECEDENS, C. CHAPELIERI, and C. VERTICILLATUM, have been tested for molluscicidal activity against BIOMPHALARIA GLABRATA. All seed extracts showed significant activity. The major constituents of the most active CALOPHYLLUM species were examinated. Some related coumarinic derivatives were synthesized in order to improve the biological activity. Among the compounds prepared, 5,7-dihydroxy-6-(2-methylbutyryl)-4-phenylcoumarin presented an interesting molluscicidal activity.</description><subject>Animals</subject><subject>Biomphalaria - drug effects</subject><subject>Flavonoids - chemical synthesis</subject><subject>Flavonoids - isolation & purification</subject><subject>Flavonoids - pharmacology</subject><subject>Lactones - chemical synthesis</subject><subject>Lactones - isolation & purification</subject><subject>Lactones - pharmacology</subject><subject>Madagascar</subject><subject>Molluscacides - chemical synthesis</subject><subject>Molluscacides - isolation & purification</subject><subject>Molluscacides - pharmacology</subject><subject>Plants - chemistry</subject><issn>0032-0943</issn><issn>1439-0221</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kDtPwzAURi0EKuUxMiL5B2C4thMnYasqXqItQ2GOXNshrpK4ip1K2fjppASJiekO39GR7kHoisIthTi-84QBCJIJytPsCE1pxDMCjNFjNAXgjEAW8VN05v0WgEYZwARNqGCQRNEUfS1dVXVeWWW1rPDcNT7Y0JkmeOwKPJeV25X9gNS4aF2Nl1LLT-mVbO_xTAW7t6E_gGtXG7ySoWsHi2w0XvdNKE2wCq-MKyq5d42z2v9sr6WpKqmCa4y_QCeFrLy5_L3n6OPx4X3-TBZvTy_z2YIozuJAYim0KFSaUJ5IDhkHppWgKom5goixGIzQqWKF3qQx3yjOY8NEwZOIRkKrjJ8jMnpV67xvTZHvWlvLts8p5IeQuc8PIfMx5MBfj_yu29RG_9FjuWG_GfdQWlObfOu6thke-Ef3DfZsfdI</recordid><startdate>19920201</startdate><enddate>19920201</enddate><creator>Ravelonjato, Bernard</creator><creator>Libot, Francine</creator><creator>Ramiandrasoa, Florence</creator><creator>Kunesch, Nicole</creator><creator>Gayral, Philippe</creator><creator>Poisson, Jacques</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19920201</creationdate><title>Molluscicidal Constituents of Calophyllum from Madagascar: Activity of Some Natural and Synthetic Neoflavonoids and Khellactones</title><author>Ravelonjato, Bernard ; Libot, Francine ; Ramiandrasoa, Florence ; Kunesch, Nicole ; Gayral, Philippe ; Poisson, Jacques</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c325t-5a6d6fc87137a309302dc61c753c042250e6d8c2fdb853bc335e26f374146dc93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Animals</topic><topic>Biomphalaria - drug effects</topic><topic>Flavonoids - chemical synthesis</topic><topic>Flavonoids - isolation & purification</topic><topic>Flavonoids - pharmacology</topic><topic>Lactones - chemical synthesis</topic><topic>Lactones - isolation & purification</topic><topic>Lactones - pharmacology</topic><topic>Madagascar</topic><topic>Molluscacides - chemical synthesis</topic><topic>Molluscacides - isolation & purification</topic><topic>Molluscacides - pharmacology</topic><topic>Plants - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ravelonjato, Bernard</creatorcontrib><creatorcontrib>Libot, Francine</creatorcontrib><creatorcontrib>Ramiandrasoa, Florence</creatorcontrib><creatorcontrib>Kunesch, Nicole</creatorcontrib><creatorcontrib>Gayral, Philippe</creatorcontrib><creatorcontrib>Poisson, Jacques</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Planta medica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ravelonjato, Bernard</au><au>Libot, Francine</au><au>Ramiandrasoa, Florence</au><au>Kunesch, Nicole</au><au>Gayral, Philippe</au><au>Poisson, Jacques</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Molluscicidal Constituents of Calophyllum from Madagascar: Activity of Some Natural and Synthetic Neoflavonoids and Khellactones</atitle><jtitle>Planta medica</jtitle><addtitle>Planta Med</addtitle><date>1992-02-01</date><risdate>1992</risdate><volume>58</volume><issue>1</issue><spage>51</spage><epage>55</epage><pages>51-55</pages><issn>0032-0943</issn><eissn>1439-0221</eissn><abstract>Abstract
Crude extracts of seeds, leaves and barks of four Madagascan CALOPHYLLUM species: C. INOPHYLLUM, C. RECEDENS, C. CHAPELIERI, and C. VERTICILLATUM, have been tested for molluscicidal activity against BIOMPHALARIA GLABRATA. All seed extracts showed significant activity. The major constituents of the most active CALOPHYLLUM species were examinated. Some related coumarinic derivatives were synthesized in order to improve the biological activity. Among the compounds prepared, 5,7-dihydroxy-6-(2-methylbutyryl)-4-phenylcoumarin presented an interesting molluscicidal activity.</abstract><cop>Germany</cop><pmid>1620744</pmid><doi>10.1055/s-2006-961389</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0032-0943 |
| ispartof | Planta medica, 1992-02, Vol.58 (1), p.51-55 |
| issn | 0032-0943 1439-0221 |
| language | eng |
| recordid | cdi_crossref_primary_10_1055_s_2006_961389 |
| source | MEDLINE; Thieme Connect Journals |
| subjects | Animals Biomphalaria - drug effects Flavonoids - chemical synthesis Flavonoids - isolation & purification Flavonoids - pharmacology Lactones - chemical synthesis Lactones - isolation & purification Lactones - pharmacology Madagascar Molluscacides - chemical synthesis Molluscacides - isolation & purification Molluscacides - pharmacology Plants - chemistry |
| title | Molluscicidal Constituents of Calophyllum from Madagascar: Activity of Some Natural and Synthetic Neoflavonoids and Khellactones |
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