Iodine as an Efficient Catalyst for One-Pot Multicomponent Synthesis of β-Acetamido Ketones

Abstract Iodine efficiently catalyzes the three-component coupling of aromatic aldehydes, enolizable ketones or keto esters, and acetonitrile in the presence of acetyl chloride to afford β-acetamido ketones in good yields at room temperature.

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Veröffentlicht in:	Synlett 2006-07, Vol.2006 (11), p.1756-1758
Hauptverfasser:	Das, Biswanath, Reddy, K. Ravinder, Ramu, R., Thirupathi, P., Ravikanth, B.
Format:	Artikel
Sprache:	eng
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creator	Das, Biswanath Reddy, K. Ravinder Ramu, R. Thirupathi, P. Ravikanth, B.
description	Abstract Iodine efficiently catalyzes the three-component coupling of aromatic aldehydes, enolizable ketones or keto esters, and acetonitrile in the presence of acetyl chloride to afford β-acetamido ketones in good yields at room temperature.
doi_str_mv	10.1055/s-2006-944208
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title	Iodine as an Efficient Catalyst for One-Pot Multicomponent Synthesis of β-Acetamido Ketones
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