Pheophorbide a, a major antitumor component purified from Scutellaria barbata, induces apoptosis in human hepatocellular carcinoma cells

Abstract SCUTELLARIA BARBATA has long been used as a Chinese medicine for the treatment of liver diseases such as hepatitis and hepatocellular carcinoma. In the present study, a bioassay-guided method was used to isolate the most active components from SCUTELLARIA BARBATA. The anti-proliferative eff...

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Veröffentlicht in:	Planta medica 2006-01, Vol.72 (1), p.28-33
Hauptverfasser:	Chan, J.Y.W, Tang, P.M.K, Hon, P.M, Au, S.W.N, Tsui, S.K.W, Waye, M.M.Y, Kong, S.K, Mak, T.C.W, Fung, K.P
Format:	Artikel
Sprache:	eng
Schlagworte:	anticarcinogenic activity Antineoplastic Agents, Phytogenic - analysis Antineoplastic Agents, Phytogenic - pharmacology Antineoplastic Agents, Phytogenic - therapeutic use apoptosis Apoptosis - drug effects Biological and medical sciences Blotting, Western Carcinoma, Hepatocellular - drug therapy Cell Line, Tumor Cell Proliferation - drug effects Chemical Fractionation chemical structure Chlorophyll - analogs & derivatives Chlorophyll - analysis Chlorophyll - pharmacology Chlorophyll - therapeutic use cultured cells cytotoxicity DNA Fragmentation Flow Cytometry General pharmacology Humans Medical sciences medicinal plants Molecular Structure Original Paper Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments pheophorbide phytochemicals Plant Extracts - chemistry Plant Extracts - pharmacology Plant Extracts - therapeutic use Scutellaria Scutellaria - chemistry Scutellaria barbata traditional medicine
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