Up regulation of CYP1B1 is an early event in gastro-oesophageal reflux mediated oesophageal injury

Background: Cytochrome P450 1B1 (CYP1B1) catalyzes activation of various carcinogens and has been implicated in early carcinogenesis in various epithelial cancers. Gastro-oesophageal reflux can potentiate malignant changes in oesophageal mucosa and it is hypothesized that CYP1B1 is up-regulated in t...

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Hauptverfasser: Menezes, AAC, Bonde, P, Swarbrick, C, Knipe, A, Bell, Z, McKeown, SR, Robson, T, Khosraviani, K, Hirst, DG, Campbell, FC, McGuigan, JA
Format: Tagungsbericht
Sprache:eng ; ger
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