Silencing of a death associated protein kinase as a pro-survival factor in colon cancer cells

Aims: Cyclooxygenase-2 (COX-2) regulates apoptosis in colorectal cancer. We previously identified DRAK2, a pro-apoptotic 'death associated' kinase, as negatively regulated by COX-2 both in-vitro and in-vivo. We aimed to characterise the role of DRAK2 at a cellular level in regulating survi...

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Hauptverfasser:	Doherty, GA, Byrne, SM, Austin, SC, Scully, GM, Kay, EW, Murray, FE, Fitzgerald, DJ
Format:	Tagungsbericht
Sprache:	eng ; ger
Online-Zugang:	Volltext
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