A Versatile Method for the Synthesis of Benzimidazoles from o-Nitroanilines and Aldehydes in One Step via a Reductive Cyclization

ABSTRACT A highly efficient and versatile method for the synthesis of benzimidazoles was achieved in one step via the Na 2 S 2 O 4 reduction of O-nitroanilines in the presence of aldehydes. Heating a solution of O-nitroaniline (1C) and an aldehyde in EtOH or another appropriate solvent, in the prese...

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Veröffentlicht in:	Synthesis (Stuttgart) 2005-01, Vol.2005 (1), p.47-56
Hauptverfasser:	Yang, Donglai, Fokas, Demosthenes, Li, Jingzhou, Yu, Libing, Baldino, Carmen M.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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