Asymmetric Synthesis of Polyfunctionalized Pyrrolidines and Related Alkaloids

Asymmetric Synthesis of Polyfunctionalized Pyrrolidines and Related Alkaloids

Abstract This account describes our recent studies on the development of a general method of preparing polyfunctionalized pyrrolidine, indolizidine, pyrrolizidine and pyrrolo[1,2-A]azepines and their related alkaloids. 1 Introduction 2 Tandem Vinyl Epoxide Aminolysis/Ring-Closing ­Metathesis 3 All R...

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Veröffentlicht in:Synlett 2004-12, Vol.2004 (15), p.2670-2680
Hauptverfasser: Pyne, Stephen G., Davis, Andrew S., Gates, Nicole J., Hartley, Joseph P., Lindsay, Karl B., Machan, Theeraphan, Tang, Minyan
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container_end_page 2680
container_issue 15
container_start_page 2670
container_title Synlett
container_volume 2004
creator Pyne, Stephen G.
Davis, Andrew S.
Gates, Nicole J.
Hartley, Joseph P.
Lindsay, Karl B.
Machan, Theeraphan
Tang, Minyan
description Abstract This account describes our recent studies on the development of a general method of preparing polyfunctionalized pyrrolidine, indolizidine, pyrrolizidine and pyrrolo[1,2-A]azepines and their related alkaloids. 1 Introduction 2 Tandem Vinyl Epoxide Aminolysis/Ring-Closing ­Metathesis 3 All Routes Lead to Oxazolidinones 4 SYN-Dihydroxylation Reactions of 2,5-Dihydropyrroles, ­Indolizidines and Pyrrolo[1,2-C]oxazol-3-ones 5 Asymmetric Synthesis of Swainsonine and Epiaustralines 6 Synthesis of 1,2-Amino Alcohols and Putative Uniflorine A Using the Petasis Reaction 7 Croomine Revisited
doi_str_mv 10.1055/s-2004-834801
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